Director, Formulation Sciences

AbbVie in Libertyville, IL

  • Industry: Pharmaceutical/Biotechnology - Others
  • Type: Full Time
position filled
The primary purpose of this role is to manage the interface between Abbvie’s drug product development group and our US-based NCE discovery organization.  This individual will collaborate with partners in DMPK, preclinical safety, process chemistry and analytical R&D to influence discovery programs and drive selection of the best candidates for clinical development.  To accomplish this goal, this individual will lead a group of approximately 20 scientists across three sites who are responsible for molecule characterization, preclinical formulation and data interpretation to guide discovery candidate selection.  The successful candidate will work collaboratively with other leaders in discovery, development, CMC, clinical and external partners to advance molecules through clinical PoC. As a member of the global formulation sciences leadership team, the position will also be responsible for ensuring formulation research is aligned with broad business objectives to guide technical innovations that improve the capabilities and productivity of the greater organization. Key Responsibilities: Responsible for ensuring developability of candidates advancing through the NCE discovery portfolio. Member of the Global NCE-Formulation Sciences Leadership Team Manages and develops resources across multiple disciplines and/or projects to address current and future business needs Ensures scientific expertise and efficient processes are in place to deliver on goals Drives and communicates strategy, balances resources and resolves issues as needed to advance programs Expertise in field is sought within company and externally within discipline.  Uses expertise to generate external contacts and collaborations. Leads Leaders.  Fosters scientific and professional development of staff. Identifies, evaluates and proposes multidisciplinary collaborations. PhD with 12+ years of related work experience; or MS or PharmD with 18+ years of related work experience; or BS with 20+ years of related work experience. Managerial experience. Demonstrated record of implementing in silico and high throughput experimental techniques to effectively guide early discovery programs is highly desired. Early evaluation of biopharmaceutical properties to enable oral delivery. Knowledge of preclinical formulation strategies to evaluate efficacy and safety of molecules. Demonstrated ability to mentor, lead and develop scientists. Experience evaluating drugability in ‘beyond the rule of five’ chemical space. Experienced in the use of prodrugs to improve biopharmaceutical properties. Excellent communication and ability to influence partners in discovery and development

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